Giuseppe Campiani Selected Research

4- acetoxy- 5- (1- (naphthyl))naphtho(2,3- b)pyrrolo(2,1- d)(1,4)oxazepine

8/2013	PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.
1/2013	The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells.
12/2010	Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells.
4/2008	A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin.

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Giuseppe Campiani Research Topics

Disease

25	Neoplasms (Cancer) 05/2022 - 06/2005
7	Infections 11/2019 - 01/2002
6	Carcinoma (Carcinomatosis) 05/2022 - 11/2005
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2003
6	Malaria 04/2021 - 03/2008
6	Neuroblastoma 01/2021 - 02/2014
5	Catalepsy 11/2014 - 01/2002
4	Epilepsy (Aura) 01/2022 - 01/2003
4	Breast Neoplasms (Breast Cancer) 07/2016 - 11/2005
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 04/2009 - 05/2002
3	Pain (Aches) 01/2022 - 08/2012
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2003
3	Polyploidy 07/2010 - 04/2007
2	Central Nervous System Diseases (CNS Diseases) 01/2022 - 03/2019
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 01/2003
2	Multiple Sclerosis 01/2022 - 01/2016
2	Seizures (Absence Seizure) 01/2021 - 11/2017
2	Idiopathic Pulmonary Fibrosis 01/2021 - 01/2020
2	Rett Syndrome (Rett's Disorder) 01/2020 - 01/2018
2	Leishmaniasis 06/2019 - 01/2016
2	Hypersensitivity (Allergy) 10/2018 - 01/2016
2	Colorectal Neoplasms (Colorectal Cancer) 01/2016 - 08/2013
2	Hematologic Neoplasms (Hematological Malignancy) 08/2013 - 04/2009
2	Leukemia 04/2007 - 09/2004
1	Squamous Cell Carcinoma of Head and Neck 05/2022
1	Starvation 05/2022
1	Parasitic Diseases (Parasitic Disease) 04/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022
1	Stroke (Strokes) 01/2022
1	Huntington Disease (Huntington's Disease) 01/2022
1	Lung Diseases (Lung Disease) 01/2022
1	Parkinson Disease (Parkinson's Disease) 01/2022
1	Pathologic Processes 01/2022
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2021
1	Temporal Lobe Epilepsy 01/2021
1	Schistosomiasis (Bilharziasis) 10/2020
1	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2020
1	Blindness (Hysterical Blindness) 01/2020
1	Macular Degeneration (Age-Related Maculopathy) 01/2020
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020
1	Rare Diseases (Rare Disease) 01/2020
1	Retinal Degeneration 01/2020
1	Extensively Drug-Resistant Tuberculosis 11/2019
1	Photophobia (Light Sensitivity) 01/2019
1	Neuralgia (Stump Neuralgia) 10/2018
1	Glioblastoma (Glioblastoma Multiforme) 12/2017

Drug/Important Bio-Agent (IBA)

15	Pharmaceutical PreparationsIBA 01/2022 - 08/2010
8	Proteins (Proteins, Gene)FDA Link 05/2022 - 02/2008
8	PBOX-6IBA 10/2016 - 09/2004
7	TubulinIBA 05/2022 - 02/2008
6	Biological ProductsIBA 01/2021 - 09/2015
4	EndocannabinoidsIBA 01/2022 - 04/2016
4	EnzymesIBA 10/2021 - 01/2016
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 02/2008
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2018 - 08/2013
4	4- acetoxy- 5- (1- (naphthyl))naphtho(2,3- b)pyrrolo(2,1- d)(1,4)oxazepineIBA 08/2013 - 04/2008
3	Histone Deacetylases (Histone Deacetylase)IBA 10/2021 - 01/2016
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2020
3	Antipsychotic Agents (Antipsychotics)IBA 11/2014 - 01/2002
2	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2020 - 01/2019
2	Retinaldehyde (Retinal)IBA 01/2020 - 01/2020
2	Histone Deacetylase 6IBA 01/2020 - 01/2020
2	ArginaseIBA 06/2019 - 01/2016
2	CarbamatesIBA 10/2018 - 09/2018
2	Antimalarials (Antimalarial Agents)IBA 04/2018 - 11/2010
2	LigandsIBA 01/2017 - 07/2016
2	Carboplatin (JM8)FDA LinkGeneric 10/2016 - 02/2014
2	Hormones (Hormone)IBA 12/2010 - 11/2005
2	Phosphotransferases (Kinase)IBA 04/2007 - 09/2004
2	Glutamic Acid (Glutamate)FDA Link 10/2003 - 01/2003
1	NitrilesIBA 04/2022
1	Cysteine Proteases (Cysteine Protease)IBA 04/2022
1	polyarginineIBA 01/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	AmidesIBA 01/2022
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2021
1	NF-kappa B (NF-kB)IBA 01/2021
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021
1	Histone Deacetylase InhibitorsIBA 11/2020
1	Praziquantel (Biltricide)FDA Link 10/2020
1	Protein Isoforms (Isoforms)IBA 04/2020
1	imetelstatIBA 01/2020
1	GoldIBA 01/2020
1	peptide deformylaseIBA 11/2019
1	QuercetinIBA 06/2019
1	Ionotropic Glutamate ReceptorsIBA 03/2019
1	artemisinin (artemisinine)IBA 01/2019
1	Ion Channels (Ion Channel)IBA 01/2019
1	HIV IntegraseIBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 10/2018
1	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 10/2018
1	1- (5- (4- bromo- 2- chlorophenyl)furan- 2- yl)- N- ((piperidin- 4- yl)methyl)methanamineIBA 04/2018
1	methylamine (methylammonium)IBA 04/2018
1	furanIBA 04/2018
1	LuciferasesIBA 12/2017
1	CannabinoidsIBA 11/2017

Therapy/Procedure

13	Therapeutics 05/2022 - 01/2003
5	Drug Therapy (Chemotherapy) 09/2013 - 07/2006